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In the shots I tried, I only had one issue where it left a bruise because I got all tense and freaked myself out so I went in the muscle
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On the cAMP pathway, U50,488 (trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide) and dynorphin A (1-17) produced a greater KOR desensitization than etorphine or levorphanol (Blake et al., 1997b)
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