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Preiss–Handler Pathway The Preiss–Handler pathway highlights the intricate process by which dietary niacin and nicotinic acid (NA) are utilized to produce NAD + (Figure 1B)

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If there is a problem with intestinal absorption, as happens with pernicious anaemia, then vitamin B12 has to be given by an injection containing hydroxocobalamin – which is retained in the body longer than cyanocobalamin