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Angiogenesis-related factors in TIF and plasma of MDA-MB-231_WT and VEGF overexpressing tumors TIF from MDA-MB-231_WT tumors contained 23 detectable factors (activin A, angiogenin, amphiregulin, angiopoietin-2, coagulation factor III (Coag Factor III), endostatin, granulocyte monocyte colony-stimulating factor (GM-CSF), heparin-binding EGF-like growth factor (HB-EGF), insulin growth factor binding protein 1 (IGFBP-1), IGFBP-3, interleukin 8 (IL-8), matrix metallopeptidase 9 (MMP-9), neuregulin 1 (NRG1-β1), pentraxin 3 (PTX-3), platelet-derived growth factor AA (PDGF-AA), placental growth factor (PlGF), pigment epithelial-derived factor (PEDF or serpin F1), plasminogen activator inhibitor 1 (PAI-1 or serpin E1), TIMP-1, TIMP metallopeptidase 4 (TIMP-4), thrombospondin-1 (TSP-1), uPA, and VEGF) from the panel of 55 (Fig
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