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European Journal of Translational and Clinical Medicine
For example, miR-145 and miR-199 have been demonstrated to decrease the expression of MITF, leading to a reduction in melanin production when hormonal signals are present [98,99,100]
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In addition, glutamine starvation triggers the impairment of the cystine/glutamate antiporter system and decreases glutathione levels in the cell [13]
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