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JPP No 5/2013 article 09
[292] Bivalent booster vaccination In August 2022, the "Pfizer-BioNTech COVID-19 Vaccine, Bivalent (Original and Omicron BA.4/BA.5)" (in short: "COVID-19 Vaccine, Bivalent") received an emergency use authorization from the US Food and Drug Administration (FDA) for use as a booster dose in individuals aged twelve years of age and older
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Reported biochemical potency against human NNMT is in the low-micromolar range with cellular EC₅₀ values in the low-micromolar range for suppression of 1-MNA and lipogenesis, with selectivity over related methyltransferases and NAD⁺-salvage enzymes [1,6,7]
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