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Once administered, mecobalamin participates directly in essential biochemical processes, including the synthesis of methionine from homocysteine and the production of myelin, the protective sheath surrounding nerve fibers that is essential for proper nerve signal transmission
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Another PET imaging study conducted in a small sample of non-opioid-dependent people found that morphine produces a very small increase in dopamine receptor occupancy (about 8%), which, however, is inversely correlated with subjective ratings of ‘high’ and other measures of reward [148]
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