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We find that CaAKG supplementation promotes longer, healthier life associated with decreased levels of inflammatory cytokines in mice
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It is possible that a longer treatment with DZnep may have affected more stable methylations such as m6A in rRNA and m5C in DNA or caused a more widespread inhibition of histone methylation, but since the period lengthening effects of DZnep are observable by 24 h we speculate these methylations may not contribute to the period lengthening
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