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Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2′-deoxyguanosine) in ex vivo human skin
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S-glutathionylation modulates intracellular signaling pathways by altering the activity of proteins—in particular, MEKK1 (mitogen-activated protein kinase kinase 1), protein tyrosine phosphatase 1B, and Ras proteins
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