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In addition, AZD2858 induced the upregulation of signaling pathways like Hippo and p53, which play a key role in cell cycle arresting and in inducing apoptotic cell death by increasing the levels of p21, the growth arrest, and DNA-damage-inducible protein (GADD45G) gamma, sestrin 3, the Fas cell surface death receptor, and caspase-3
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Animal Model:Fischer male rats (300-400 g) [1] Dosage:1.5 g/kg (Pharmacokinetic Analysis) Administration:Injected simultaneously i.p
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