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5.4 Wound healing BSPs exhibit significant wound-healing bioactivity, mediated primarily through activation of the TGF-β/Smad signaling pathway ( P 0.05) and showed no significant difference in hepatic TG accumulation versus controls, collectively confirming BSP’s metabolic safety and minimal hepatotoxic potential at these doses ( Collectively, although research on the structure–function relationship of BSPs has burgeoned, comprehensive toxicological profiling remains nascent
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