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niger , were found to produce a soluble complement-inhibitory factor, potentially lipid derived, that prevented alternative pathway activation (219, 221)
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Mice with TNF receptor 1 (TNFR1) knockout showed resistance to ISO-induced cardiac injury, marked by downregulated expression of IL-1 ฮฒ, iNOS, NF-ฮบB, and AP-1 (208)
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