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A control cohort of patients treated with 0.4 mg/kg pegadricase alone, mimicking Cohort 3 from the Phase 1a study, showed a transient drop in sUA for 7 days that rebounded back to baseline levels by day 30 in four of five patients (red symbols, Fig
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[DOI] [PubMed] [Google Scholar] Donner 2002 Donner A, Klar N
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