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Notably, the first KRAS (G12C) inhibitor, LY3499446, from Eli Lilly, has been discontinued due to safety concerns, but at the 2021 AACR meeting, they presented preclinical results for another inhibitor, LY3537982
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BMP type I receptors include activin-like kinase 1 (ALK1), ALK2, ALK3, and ALK6
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