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In addition, keratin-related genes have also been implicated in immune responses, such as KRT1 regulates innate immunity by controlling IL-18 release 13 and abnormal expression of keratin genes like KRT6 , KRT16 , and KRT17 is observed in psoriatic lesions, leading to increased keratinocyte proliferation, and heightened inflammation 14,15,16,17,18,19
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2021;118:e1921828118
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