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For instance, (He et al., 2021), showing that TSG could suppress the production of pro-inflammatory cytokines, such as TNF-α, IL-1β, and IL-6, and enhance the level of anti-inflammatory cytokine IL-10, indicated a potential effect of this compound on suppressing the NF-κB signaling pathway since the production of pro-inflammatory cytokines tested in this study is all dependent on the activation of NF-κB

It naturally occurs in red meat and other animal source foods