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Based on a series of structurally characterized sdAbs, they assessed antibodies substituted with reactive ncAAs, AzF (for photo-cross-linking) and OBeY (for spontaneous cross-linking) combined with systematic evaluations in yeast display format of over 40 ncAA-substituted variants, multiple clones that retained binding function were discovered while gaining UV-mediated or spontaneous cross-linking abilities
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[DOI] [PMC free article] [PubMed] [Google Scholar] 330.Diener, C., Keller, A
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