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High T3 levels are related to increased myocardial contractility and electrical conduction, and arrhythmias events, while low T3 promotes opposite effects, such as bradycardia ( The heart is able to locally adjust the metabolism of TH through the modulation of D3 activity, as described in myocardial infarction (76) and dilated cardiomyopathy (77)
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Afterwards, 10 µmol/l CD39 and 10 µmol/l CD73 (Sigma, USA) were prepared with Tris–HCl buffer (50 mmol/l, pH = 7.4) and mixed at equal volumes
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