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25% at 3-9mg escalation) Fatigue: ~26.9% pooled (42.6% at 9mg) · Vomiting: ~8.2% pooled Discontinuation due to AEs: ~10% pooled (21% at 6mg) vs ~8% placebo Alopecia: ~9.3% at 9mg Petrelintide (Zealand/Roche) — ZUPREME-1 (maximally effective arm): Vomiting: 0% · GI-related discontinuation: 0% Diarhhea: 1.0% Constipation: 2.3% Total AE-related discontinuation: 4.8% (vs 4.9% placebo) Even acknowledging cross-trial limitations, petrelintide's profile stands out — particularly the zero vomiting and zero GI discontinuations

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Furthermore, since BPC-157 is shown to accelerate recovery in many preclinical musculoskeletal injury models, it is likely used far out of competition, as opposed to EPO and HGH