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Taken together, the competent T-cell responses observed in the H4R −/− , HDC −/− , and HDC −/− BMMC-reconstituted Sash mice suggest the histamine/H4R axis is not required for adaptive T-cell responses in these colitis models
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Additionally, diets rich in carnosine sources, such as beef or chicken, might offer some protection against histamine's adverse effects
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