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Paternal obesity initiates metabolic disturbances in two generations of mice with incomplete penetrance to the F2 generation and alters the transcriptional profile of testis and sperm microRNA content
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In yeast and mammalian cells, disproportionate increases in cytoplasmic volume relative to genome content reduce the effective concentration of DNA-encoded templates and their products, leading to impaired maintenance of protein and mRNA concentrations and reduced growth capacity (Neurohr et al., 2019
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