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Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate: Structure
It is estimated that of all phase I trials, roughly 63% make it to phase II, 31% make it to phase III, and only 9.6% make it through the entire three-stage trial (5)
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10.1038/nri3399 152 KonigsbergerS.Peckl-SchmidD.ZaborskyN.PatzakI.KieferF.AchatzG
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