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These interventions utilize FMT from a healthy donor to modify the gut microbiome of subjects in various stages of liver disease and alleviate gut dysbiosis and immune dysfunction (see and In fact, a pilot study has shown promising results of FMT in subjects with hepatic encephalopathy (79)
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Therefore, the risk-benefit profile remains an important consideration for the treatment of patients with tucatinib, even in late stages of disease
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