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The lipid-lowering effects of garlic are largely attributed to OSCs that affect hepatic lipid metabolism by inhibiting key enzymes involved in cholesterol and fatty acid biosynthesis, such as HMG-CoA reductase, fatty acid synthase, and acetyl-CoA carboxylase (Figure 3)
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VF-13, a chimeric peptide combining the pharmacophores of the endogenous cannabinoid peptide VD-hemopressin (α) and neuropeptide FF [223], was pharmacologically evaluated for analgesic activity
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