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Recombinant erythropoietin has a reported half-life of roughly 4-13 hours intravenously but appreciably longer subcutaneously, because absorption from the subcutaneous depot becomes slower than elimination
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345 , 346 In yet another example, the Mitragrotri laboratory adapted the VBP and CBP peptides to decorate hyaluronic acid (HA) polymer to create a system termed Hemostatic Agents via Polymer Peptide Interfusion (HAPPI) that, when intravenously delivered, could target the injury site and bind to exposed vWF and collagen for hemostatic action
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