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By quenching superoxide and converting it back to ground-state oxygen, while simultaneously scavenging and deactivating peroxyl radical intermediates, AX effectively mitigates oxidative damage within the mitochondria [48,49]
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RNA sequencing of giredestrant and palbociclib treated cells, and proteomic analysis of palbociclib treated cells identified pathways consistent with oxidative stress and increased lipid peroxidation (Fig
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