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METAOD005: A Phase IIb (randomized, double-blind, placebo-controlled) study to assess the efficacy (reduction in body weight), safety and tolerability of 12 weeks treatment with daily doses (1, 5, 10, 20 or 30 mg AOD9604) administered orally (capsules) in 300 healthy, clinically obese males, and females of non-child bearing potential, with a BMI ≥ 35 kg/m 2
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Indirect effects occur via the induction of autoimmunity or chronic inflammation, particularly in the context of Long COVID, whereby persistent spike protein and/or immune complexes may drive symptoms and pathogenesis
energy metabolism* Vitamin B12 is needed to synthesize hemoglobin
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