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In vivo cortical glutathione response to oral fumarate therapy in relapsing-remitting multiple sclerosis: A single-arm open-label phase IV trial using 7-Tesla 1H MRS - ScienceDirect

For example, Golbe et al reported that age of onset in individuals carrying the A53T alpha-synuclein (PARK1) mutation is positively associated with a GSTpi G-for-A nucleotide substitution at position 313 [159], while McCormick et al identified polymorphisms in GSTpi that correlate with increased risk of PD after exposure to pesticides [160]

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Cytokines and chemokines play a crucial role in driving inflammation through their ability to activate endothelial cells, recruit immune cells to the synovial chamber, stimulate fibroblasts, and facilitate the accumulation of activated T and B cells