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GSH depletion induces upregulation of genes involved in detoxification and DNA synthesis To establish whether or not reduced GSH levels affects the expression of genes involved in oxidative detoxification and DNA synthesis, the mRNA levels of the superoxide dismutase ( sod) , glutaredoxin ( grx) and ribonucleotide reductase ( rnr) genes were determined in the pbggcs-ko2 , the pbgr - ko1 and the WT parasites

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The treatment given to this patient resulted in an improved microbiome with an increase in bacterial diversity, partly due to an increase in the relative abundance of butyrate-producing bacterial species, which were paralleled by an increase in butyrate concentration, an anti-inflammatory SCFA (Engen et al., 2020)