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The TB-500 fragment is studied as an isolated probe of this actin-binding motif
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“In this work we have shown that 5 days of administration of gold nanoparticles functionalized with glutathione and coated with lithium (called LiG-AuNPs) can significantly inhibit the activity of GSK-3β kinase in the hippocampus of mice, and that the same treatment repeated for 2 months leads to a significant regression of the memory deficit exhibited by a mouse model of Alzheimer's disease, analyzed at the behavioral and molecular levels," said Giulia Puliatti, one of the study’s authors
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