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Cepharanthine hydrochloride can serve a role in reversing drug resistance in ovarian cancer via inhibiting the expression of ABCB1, and reducing the mRNA and protein expression levels of P-gp, which may be caused by inhibiting the PI3K/Akt signaling pathway (132)
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Serine metabolism: cross-communicating metabolism between astrocytes and neurons L-serine and D-serine, the amino acids akin to glutamine, play a fundamental role in neuron–glia communication (Wolosker, 2011)
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