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Botulism , another NMJ disorder, presents with acute paralysis and can mimic GBS, with distinct features including descending paralysis and mydriasis
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Given that systemic inflammation and peripheral immune dysregulation are emerging as shared hallmarks of neurodegeneration, applying this sc-eQTL-anchored approach to other disorders may reveal conserved or disease-specific immune-regulatory hubs, facilitating the discovery of broad-spectrum immunomodulatory therapies
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