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Introduction Human induced pluripotent stem cell (iPSC)-derived hepatocyte-like cells (HLCs) present a unique opportunity for translational medicine ( in vitro modeling of the liver but cost, accessibility and variability between batches is a major drawback ( in vivo embryonic liver developmental stages: endoderm, hepatoblast and hepatocyte maturation ( in vitro modeling is the variation in line differentiation capacity and outcomes
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When a significant interaction was found, follow-up analyses were performed using two-way or one-way repeated measures ANOVAs with Bonferroni corrections and pair-wise comparisons
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